Phytochemical investigation of the n-BuOH extract of Scilla lingulata using LC-ESI/MS technique, enriched with molecular docking studies
| dc.contributor.author | BENRAMDANE, Zeyneb | |
| dc.date.accessioned | 2020-12-23T10:03:31Z | |
| dc.date.available | 2020-12-23T10:03:31Z | |
| dc.date.issued | 2020-09 | |
| dc.description.abstract | In this work, we mainly focused on the phytochemical study of the endemic Algerian species, Scilla lingulata Poir. (Asparagaceae), in order to structurally identify its chemical composition. The use of the analytical LC-ESI / MS technique, allowed us to investigate the phytoconstituents, especially the polar compounds, present in the n-butanolic extract of this plant. Profound analysis in the UV-Vis and ESI / MS spectra (in positive and negative mode) allowed us to elucidate the structure of ten glycosylated flavonoids (flavone type). The in silico assays of those latter were carried out by means of molecular docking to evaluate the anti-Alzheimer and anti-inflammatory activities of these molecules. | en_US |
| dc.identifier.uri | http://dspace.univ-msila.dz:8080//xmlui/handle/123456789/22656 | |
| dc.language.iso | en | en_US |
| dc.publisher | UNIVERSITE MOHAMED BOUDIAF - M’SILA | en_US |
| dc.subject | n-butanolic extract of Scilla ligulata, UV-Vis, LC-ESI/MS, glycosylated flavonoids, Molecular docking, in silico, Anti-Alzheimer activity, Anti-inflammatory activity. | en_US |
| dc.title | Phytochemical investigation of the n-BuOH extract of Scilla lingulata using LC-ESI/MS technique, enriched with molecular docking studies | en_US |
| dc.type | Thesis | en_US |
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